Sylvie PDRN Salmon DNA Serum pen
Before and after two weeks
Plumper-looking skin in 2 weeks: visibly plumper cheeks, dewy from the first pump, powered by salmon DNA
Plumping ingredients: salmon DNA (PDRN), caviar water and an airless pen
Results percentages
How it works: three pumps a day, 90 pumps in each pen
Sylvie vs. the clinic: salmon DNA, no needles or downtime, under $1 a day, 30-day money-back guarantee
Woman holding the Sylvie pen to her cheek
Try it risk-free: 30-day money-back guarantee
A month of salmon DNA, in one pen
Margaret, 58, holding the sylvie penJennifer, 61, holding the sylvie penCustomer photo
Margaret and 12,000+ others purchased
4.8/5 (1,214 reviews)

PDRN Salmon DNA SerumFor skin after menopause

$117.00 $66.00 Bestseller
Plumper-looking skin in 2 weeks
Dewy from the first pump
3 measured pumps a day
No needle. No clinic bill.

Say goodbye to dry, crepey skin after menopause. This salmon DNA serum pulls water back into your skin, so it looks plumper and smoother in two weeks.

1 Pen
30-day supply · 90 pumps
$39.00
$59.00
Buy 2, Get 1 FREE SAVE $51
90-day supply · $22.00 per pen
$66.00
$117.00
+ 1 FREE Pen (30 more days)$39
+ FREE Shipping
Buy 3, Get 3 FREE BEST VALUE
180-day supply · $14.50 per pen
$87.00
$234.00
● In stock, on its way by TuesdayFREE tracked shipping
Refills every 90 days: 3 pens for $66
Skip, pause or cancel anytime
Free shipping on every refill
30-day guarantee
Needle-free
Tracked shipping
Secure checkout
Selling out fast
Due to high demand, limited quantities available. Buy 2, Get 1 Free ends when this batch is gone.
89% soldEnds in 03:45:59
30
30-day money-back guarantee
Give it an honest try. If you’re not happy with how your skin looks, email us within 30 days of delivery and we’ll make it right.
Plumper in 2 weeksDewy from the first pump3 measured pumps a dayNo needle, no clinic bill90 pumps = 30 daysAirless, nothing wasted30-day guarantee
As featured in
VOGUEAllureELLEBAZAARWomen's HealthByrdie

Loved by 12,000+.

4.8/5 from 1,214 verified reviews · See all
Margaret, 58
Margaret, 58★★★★★
✓ Verified purchase
"I had resigned myself to my face just looking thinner after menopause. Two weeks of three clicks a day and my cheeks look full again. My daughter asked what I changed."
Deborah, 52
Deborah, 52★★★★★
✓ Verified purchase
"I was quoted $199 for one salmon DNA session. This pen has done more for the look of my skin than that would have, and I never had to sit in a clinic."
Jennifer, 61
Jennifer, 61★★★★★
✓ Verified purchase
"Every PDRN serum I tried ended up sticky and stuck in the cap. The pen just clicks. Same amount every day, and my skin is plumped, soft and glowy."
Linda, 55
Linda, 55★★★★★
✓ Verified purchase
"Dewy from day one, and the crepey look on my neck is softer by week three. I use the same three pumps for face and neck."
Day 1Day 1
Day 14Day 14

The serum that puts the plump back.

Your skin didn't fail. It changed. When estrogen drops, it holds less water and loses its bounce. Your moisturizer keeps it comfortable, but it was made for general ageing skin, not skin after menopause.

Plumper in 2 weeks Dewy in hours Holds water all day
Buy 2, Get 1 Free · 30-day money-back guarantee

How does it work?

Salmon DNA (PDRN) is what med spas charge $199 a session for. It pulls water into the surface of your skin, so it looks plumper and dewier: the exact thing falling estrogen took away.

It works as a small thing done every day, not a treatment booked twice a year. So Sylvie seals it in an airless pen. Click three times, once a day, and you get the same amount every morning.

The pen holds exactly 90 pumps. When it's empty, your month is done.

3 pumps, once a day 90 pumps = 30 days
Three pumps of serum on a fingertip
The clinic alternative

Skip the $1,000 salmon DNA facial. Try the 30-day pen first.

Med spas sell salmon DNA one needle and one bill at a time: $199 for a first session, close to $1,000 for the full facial. Same ingredient. Sylvie is 73¢ a day, with no needle and 30 days to change your mind.

One clinic session
$199
then book again
Sylvie, 90 days
73¢ /day
$66 for 3 pens, at home
Med spa poster for a $199 salmon DNA facial
The sylvie pen on a tray

Real results.

94%
Said skin looked dewier from the first week
Based on a 4-week customer panel
91%
Said cheeks looked plumper by day 14
Based on a 4-week customer panel
88%
Would pick the pen over a clinic visit
Based on a 4-week customer panel

Why Sylvie?

Sylvie
Clinic PDRN
Dropper serums
Made for skin after menopause
✓
✗
✗
Salmon DNA (PDRN)
✓
✓
✓
Same dose every day
✓ 3 measured pumps
Per visit only
✗ Guesswork
Needle-free
✓
✗
✓
Cost for 90 days
$66.00
$597+
$60–$180
Money-back guarantee
30 days
✗
Rarely
In stock · Ships by Tuesday

What happens when you use it every day.

Three pumps a day. Here’s what to look for.

Days 1–3
Dewy, within hours
Water is drawn into the surface. Skin looks fresher in the mirror the same day.
Day 14
Plumper, smoother
Cheeks look fuller and texture reads smoother. This is the mark most women notice.
Day 30
Bounce that stays
Skin holds on to water through the day instead of looking flat by afternoon. Keep going: the daily habit is what keeps it.

What's in the pen.

Two ingredients. The one clinics use, and the one that makes it feel like a treat.

Salmon DNA (PDRN)
Salmon DNA (PDRN)
Listed as Sodium DNA. Draws water into the surface so skin looks plumper, and helps improve the look of elasticity with daily use.
Caviar Water
Caviar Water
Lipids and amino acids for the dewy look, and comfort for dry, dull skin.

Your questions, answered.

4.8 · 1,214 reviews
Three clicks of serum onto a fingertip
Pressing serum into the cheek
Sweeping serum down the neck
Customer smiling with the pen
Dewy skin after using the pen
Loved by our customers
Buy 2, Get 1 Free · Ends tonight

Start your 90-day supply today.

Ships by Tuesday. Free shipping. 30 days to decide.

30-day money-back guarantee